A insurance claim that the combination of Motrin and also Robitussin brand medications causes heart strikes in kids has not been created by reliable clinical evidence.

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Published11 February 2009

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We first received an admonition not to integrate Motrin v Robitussin via email in December 2008:

Medicine interaction!

Madison, period 8, happen away simply a couple of days ago. We’ve to be asked to happen this on. Physicians told her family that there have been quite a few children Madison’s age that have died recently the same method that she did. The only common link in between them was the they were offered Motrin (ibuprofen) and also Robitussin together, this caused a heart attack.

They believe this is what happened to them. Lock told she to alert everyone to this. Perform not give children both of these medicines together. You can provide them one or the other yet not both.

When Madison broke down she suffered a heart attack and also they were able come revive her yet the ns of oxygen damaged her brain and she was put on the respirator.

After this she had four strokes before she passed away after gift taken turn off the respirator. Please pass this on.

The story the warning is framed upon, the an eight-year-old girl called Madison passed away from a heart attack and also strokes brought around by this combination of over-the-counter drugs, to be unverifiable: the account listed no information as to Madison’s surname, whereby she lived, that her physicians were, whereby she was treated, or also the day she died. Absent any of the information, do the efforts to recognize if there in reality was such a child verified a nearly impossible task.

It is feasible that a child deserve to have a heart attack. Because that example, a news report the 2 October 2007 detailed heart strikes in kids are a rare but under-recognized problem that are many likely caused by love spasms i m sorry briefly reduced off the blood supply. It thus cannot it is in ruled the end that a child referred to as Madison (of no recognized last name or address) did experience an acute myocardial infarction. However, the in rare instances youngsters have experienced heart strikes only proves that such occasions happen, no that any particular drug interaction reasons them.

The energetic ingredient in children Motrin is Ibuprofen, a nonsteroidal anti-inflammatory drug effective in relieving pain and reducing inflammation. (Ibuprofen is likewise marketed under several other brand names, such as Advil, Medipren, and Nuprin.) children Motrin Suspension first became accessible as a prescription product in 1989, and also in 1995 it to be cleared through the Food and also Drug management for marketing as an over-the-counter product. Both those landmarks developed only after the product had actually been extensively tested top top children:


Before children’s Motrin became an over-the-counter product, its safety and security profile was sustained by a landmark research involving almost 84,000 children — among the largest and also most rigorous children clinical studies ever conducted. The study covered 3 years and also included 1,735 physicians nationwide.

Robitussin Pediatric sneeze is a syrup that contains Dextromethorphan HBr, a cough suppressant. The Pediatric cough & Cold formulation includes Chlorpheniramine maleate, one antihistamine, in addition to the Dextromethorphan HBr.

We have not yet turned up any kind of studies confirming heart assaults brought around by the mix of these two over-the-counter medications, one of two people in children or adults, however that is not to say kids should be acquisition OTC cold medications. One 8 October 2008 declare by the FDA support the referral of the customer Healthcare products Association that children under the age of 4 should not be dosed v over-the-counter cough and cold products. This complies with its January 2008 advisory that these commodities not be offered in kids under the age of 2 due to the fact that of the danger of serious and also potentially life-threatening side effects.

As listed in a news report from September 2007: “An FDA review of side-effect documents filed with the company between 1969 and September 2006 found 54 reports that deaths in children associated with decongestant medications made v pseudoephedrine, phenylephrine or ephedrine. It likewise found 69 reports of deaths connected with antihistamine medicines containing diphenhydramine, brompheniramine or chlorpheniramine. Many of the deaths were kids younger 보다 2.”

The FDA offers these medication advice to the parents and also caregivers of tiny children:

Do not give kids medications labeled only for adults.Talk to your health treatment professional, such as your doctor or pharmacist, if girlfriend have any type of questions about using cough or cold medicines in children.Choose OTC cough and also cold drugs with child-resistant safety and security caps, once available. After each use, make certain to nearby the lid tightly and store the drugs out the the sight and also reach that children.Check the “active ingredients” section of the “Drug Facts” label of the drugs that you choose. This ar will aid you know what symptom the active ingredients in the medication are intended to treat. Cough and cold medicines often have an ext than one active ingredient, such together an antihistamine, a decongestant, a cough suppressant, one expectorant, or a pain reliever and fever reducer.Be really careful if you are giving much more than one medication to a child. Make certain the medicines do not have actually the same form of active ingredients. For example, perform not provide a child much more than one medicine that has actually a decongestant. If you use two medicines that have the very same or comparable active ingredients, her child might be harmed by acquiring too lot of one ingredient.Carefully follow the direction for exactly how to use the medication in the “Drug Facts” component of the label. This directions call you just how much medication to give and how often you can give it. If you have actually a question around how to usage the medicine, ask your pharmacist or other health treatment professional. Overuse or misuse the these products can bring about serious and also potentially life-threatening side effects, together as rapid heartbeat, drowsiness, breathing problems, and also seizures.Only usage measuring devices that come with the medication or those specially created measuring drugs. Carry out not use family members spoons come measure medicines for children since household spoons come in different sizes and also are not expected for measure medicines.Understand that making use of OTC cough and cold medicines does no cure the cold or cough. These drugs only treat her child’s symptoms, such together runny nose, congestion, fever, and also aches. They perform not shorten the length of time your son is sick.

In 2003, another an individual account circulated by e-mail implicated children Motrin in the formation of stomach ulcers in a boy dosed through it. Us did not encounter any type of subsequent reports of similar instances, and also no particular interaction precaution accuse exists for that medicine combination.

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On 22 December 2014, children’s Medical center of Dallas handle the recirculating rumor ~ above Twitter:

If you’ve checked out a on facebook post around Motrin and also Robitussin, please read and share this. The info in the post is not correct and also was no posted by among our employees. Us encourage caregivers to discuss any type of over-the-counter medicines with your doctor and also to ask about information uncovered on the Internet.