In our recent question and answer, we talk about the safety and security considerations when combining alcohol through fluconazole.

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patty asked

I take it a at some point fluconazole dose, 150 mg pill, for a yeast infection. Is the OK come drink alcohol 2 days later? just how long before it pipeline your system?


There is no medicine interaction in between fluconazole and also alcohol, however it usually is not recommended come drink alcohol when recovering indigenous an infection. Alcohol has the propensity to decrease immune function, at the very least acutely (1). In addition, it have the right to potentially worsen medication next effects, including:

NauseaDiarrheaUpset stomach

What Is Fluconazole?

Fluconazole, additionally known through the brand surname Diflucan, is a systemic anti-fungal the is frequently used for yeast infections and also oral thrush infections. That is typically well tolerated however has been well-known to reason headache, nausea and abdominal pain.

An amazing characteristic that fluconazole is its capability to eradicate plenty of fungal infections, consisting of vaginal fungal infections, in a single dose. This is as result of how fluconazole works and also the fairly long fifty percent life of the drug.

How walk Fluconazole Work?

Fluconazole functions by inhibiting the synthesis of a vital component (ergosterol) the the fungal cabinet membrane. A single dose the fluconazole has actually a reported half life the 30-50 hours(2). In general, a medicine takes around 5 half lives come be totally metabolized and also eliminated indigenous the body. This essentially means that the medicine is present and energetic in the body because that 6 to 10 days! that is why a solitary dose is efficient for eradicating infections.

After a single dose, symptoms tend to get better after 1 come 3 days and also the majority of infections are cleared in 7 come 10 days. The clinical cure rate with solitary doses that fluconazole is around 69%, i m sorry is why sometimes doctors will certainly recommend taking a second dose of fluconazole 7 job after the early dose.

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Problems through Alcohol and Fluconazole

In regard to acquisition alcohol after fluconazole administration, there is no drug interaction as discussed above. However, if you are experiencing any symptoms native medication use such together nausea or abdominal muscle pain, alcohol might worsen those next effects. Fluconazole big in the body for a considerable duration of time, 6 to 10 days. If you wish to totally avoid alcohol while the drug is present, girlfriend would need to wait that period of time.